While Bartimaeus sits by the roadside wondering, “Why all the commotion?” he is told that Jesus of Nazareth is passing by. In addressing Him as “O Lord, Son of David,” his crying out to Him for mercy acknowledges Christ's deity and humanity, as well as signifying his acceptance of His Messiahship as the future King of Israel. “Son of David” was a well-known designation of the expected Prophet (Ezekiel 34:23-24; Matthew 9:27; Luke 1:32), the Promised One at whose coming the eyes of the blind would be opened (Isaiah 29:18; 35:5).
The fact that their eyes can now see alludes not only to receiving physical sight, but also—more importantly—to their eyes being opened spiritually, verified by the words “and they followed Him” (Matthew 20:34; Mark 10:52; Luke 18:43). The world ridicules Christians for calling out to God in faith, but this is exactly what the Son of God wants us to do. Many who are spiritually blind to God's truth have a bitter attitude, disliking those whose eyes are opened to Christ, the only path to salvation.
Since Bartimaeus was blind, he likely felt a certain tension while straining to ascertain Jesus' reaction to his shout. No doubt, he felt great relief when He responded with compassion. Most people do not realize how far they are from God and the wonderful gifts He offers to those who respond to His call. However, because they will not cast off their self-righteousness, they remain alienated from Him, at enmity with Christ (Romans 10:3). When God calls, we must lay aside every weight and enticing sin (Hebrews 12:1-3).
— Martin G. Collins